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In this study, we carried out nonlinear finite element simulations to predict the performance of a column-tree moment connection (CTMC) under fire and static loads. We also conducted a detailed parameter study based on five input variables, including the applied temperature, number of flange bolts, number of web bolts, length of the beam, and applied static loads. The first variable is changed among seven levels, whereas the other variables are changed among three levels. Employing the Taguchi method for variables 2–5 and their levels, 9 samples were designed for the parameter study, where each sample was exposed to 7 different temperatures yielding 63 outputs. The related variables for each output are imported for the training and testing of different surrogate models. These surrogate models include a multiple linear regression (MLR), multiple Ln equation regression (MLnER), an adaptive network …